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-Structure paper
Title | Synthesis, biological evaluation and molecular investigation of fluorinated peroxisome proliferator-activated receptors alpha/gamma dual agonists |
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Journal, issue, pages | Bioorg. Med. Chem., Vol. 20, Page 2141-2151, Year 2012 |
Publish date | Feb 27, 2008 (structure data deposition date) |
![]() | Fracchiolla, G. / Laghezza, A. / Piemontese, L. / Parente, M. / Lavecchia, A. / Pochetti, G. / Montanari, R. / Di Giovanni, C. / Carbonara, G. / Tortorella, P. ...Fracchiolla, G. / Laghezza, A. / Piemontese, L. / Parente, M. / Lavecchia, A. / Pochetti, G. / Montanari, R. / Di Giovanni, C. / Carbonara, G. / Tortorella, P. / Novellino, E. / Loiodice, F. |
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Methods | X-ray diffraction |
Resolution | 2.8 Å |
Structure data | ![]() PDB-3cdp: |
Chemicals | ![]() ChemComp-YRG: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSCRIPTION / bundle of alpha-helices and a small four-stranded beta-sheet / Activator / Diabetes mellitus / Disease mutation / DNA-binding / Metal-binding / Nucleus / Obesity / Phosphoprotein / Receptor / Transcription regulation / Zinc-finger |