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TitleThymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA.
Journal, issue, pagesNat. Chem. Biol., Vol. 8, Page 328-330, Year 2012
Publish dateNov 16, 2011 (structure data deposition date)
AuthorsZhang, L. / Lu, X. / Lu, J. / Liang, H. / Dai, Q. / Xu, G.L. / Luo, C. / Jiang, H. / He, C.
External linksNat. Chem. Biol. / PubMed:22327402
MethodsX-ray diffraction
Resolution3.002 - 3.011 Å
Structure data

PDB-3uo7:
Crystal structure of Human Thymine DNA Glycosylase Bound to Substrate 5-carboxylcytosine
Method: X-RAY DIFFRACTION / Resolution: 3.002 Å

PDB-3uob:
Crystal structure of Human Thymine DNA Glycosylase Bound to Substrate Analog 2'-deoxy-2'-beta-fluoro-cytidine
Method: X-RAY DIFFRACTION / Resolution: 3.011 Å

Source
  • homo sapiens (human)
KeywordsHYDROLASE/DNA / dsDNA with 5caC / HYDROLASE-DNA complex / dsDNA

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