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Structure paper

TitleStructure of Complement C6 Suggests a Mechanism for Initiation and Unidirectional, Sequential Assembly of Membrane Attack Complex (MAC).
Journal, issue, pagesJ. Biol. Chem., Vol. 287, Page 10210-10222, Year 2012
Publish dateJul 27, 2011 (structure data deposition date)
AuthorsAleshin, A.E. / Schraufstatter, I.U. / Stec, B. / Bankston, L.A. / Liddington, R.C. / Discipio, R.G.
External linksJ. Biol. Chem. / PubMed:22267737
MethodsX-ray diffraction
Resolution2.869 Å
Structure data

PDB-3t5o:
Crystal Structure of human Complement Component C6
Method: X-RAY DIFFRACTION / Resolution: 2.869 Å

Chemicals

ChemComp-CD:
Unknown entry

ChemComp-FUL:
beta-L-fucopyranose

ChemComp-MAN:
alpha-D-mannopyranose

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / MACPF / MAC / MEMBRANE ATTACK COMPLEX / COMPLEMENT / INNATE IMMUNE SYSTEM / BLOOD / MEMBRANE / C7 / C8 / C9 / CYTOLYSIN

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