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Structure paper

TitleStructural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 19, Page 184-, Year 2012
Publish dateDec 8, 2010 (structure data deposition date)
AuthorsDou, H. / Buetow, L. / Hock, A. / Sibbet, G.J. / Vousden, K.H. / Huang, D.T.
External linksNat. Struct. Mol. Biol. / PubMed:22266821
MethodsX-ray diffraction
Resolution1.999 - 2.789 Å
Structure data

PDB-2y1m:
Structure of native c-Cbl
Method: X-RAY DIFFRACTION / Resolution: 2.67 Å

PDB-2y1n:
Structure of c-Cbl-ZAP-70 peptide complex
Method: X-RAY DIFFRACTION / Resolution: 1.999 Å

PDB-4a49:
Structure of phosphoTyr371-c-Cbl-UbcH5B complex
Method: X-RAY DIFFRACTION / Resolution: 2.214 Å

PDB-4a4b:
Structure of modified phosphoTyr371-c-Cbl-UbcH5B-ZAP-70 complex
Method: X-RAY DIFFRACTION / Resolution: 2.789 Å

PDB-4a4c:
Structure of phosphoTyr371-c-Cbl-UbcH5B-ZAP-70 complex
Method: X-RAY DIFFRACTION / Resolution: 2.704 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-K:
Unknown entry

Source
  • homo sapiens (human)
KeywordsLIGASE / UBIQUITIN RING E3 LIGASE / LIGASE/TRANSFERASE / LIGASE-TRANSFERASE COMPLEX

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