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| Title | Geometry of binding of the benzamidine- and arginine-based inhibitors N alpha-(2-naphthyl-sulphonyl-glycyl)-DL-p-amidinophenylalanyl-pipe ridine (NAPAP) and (2R,4R)-4-methyl-1-[N alpha-(3-methyl-1,2,3,4-tetrahydr quinolinesulphonyl)-L-arginyl]-2-piperidine carboxylic acid (MQPA) to human alpha-thrombin.X-ray crystallographic determination of the NAPAP-trypsin complex and modeling of NAPAP-thrombin and MQPA-thrombin. |
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| Journal, issue, pages | Eur. J. Biochem., Vol. 193, Page 175-182, Year 1990 |
| Publish date | Oct 24, 1991 (structure data deposition date) |
Authors | Bode, W. / Turk, D. / Sturzebecher, J. |
External links | Eur. J. Biochem. / PubMed:2226434 |
| Methods | X-ray diffraction |
| Resolution | 1.8 Å |
| Structure data | ![]() PDB-1ppc: |
| Chemicals | ![]() ChemComp-MID: ![]() ChemComp-CA: ![]() ChemComp-HOH: |
| Source |
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Keywords | HYDROLASE/hydrolase inhibitor / SERINE PROTEINASE / HYDROLASE-hydrolase inhibitor complex |
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