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Structure paper

TitleT cell receptors are structures capable of initiating signaling in the absence of large conformational rearrangements.
Journal, issue, pagesJ. Biol. Chem., Vol. 287, Page 13324-13335, Year 2012
Publish dateMar 7, 2011 (structure data deposition date)
AuthorsFernandes, R.A. / Shore, D.A. / Vuong, M.T. / Yu, C. / Zhu, X. / Pereira-Lopes, S. / Brouwer, H. / Fennelly, J.A. / Jessup, C.M. / Evans, E.J. ...Fernandes, R.A. / Shore, D.A. / Vuong, M.T. / Yu, C. / Zhu, X. / Pereira-Lopes, S. / Brouwer, H. / Fennelly, J.A. / Jessup, C.M. / Evans, E.J. / Wilson, I.A. / Davis, S.J.
External linksJ. Biol. Chem. / PubMed:22262845
MethodsX-ray diffraction
Resolution2.5 - 4.1 Å
Structure data

PDB-3r06:
Crystal structure of anti-mouse CD3epsilon antibody 2C11 Fab fragment
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-3r08:
Crystal structure of mouse cd3epsilon in complex with antibody 2C11 Fab
Method: X-RAY DIFFRACTION / Resolution: 4.1 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • cricetulus migratorius (Armenian hamster)
KeywordsIMMUNE SYSTEM / antibody / anti-CD3epsilon / T-cell receptor / signalling / CD3epsilon

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