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Structure paper

TitleAssembly of the Eukaryotic Plp-Synthase Complex from Plasmodium and Activation of the Pdx1 Enzyme.
Journal, issue, pagesStructure, Vol. 20, Page 172-, Year 2012
Publish dateJan 3, 2012 (structure data deposition date)
AuthorsGuedez, G. / Hipp, K. / Windeisen, V. / Derrer, B. / Gengenbacher, M. / Boettcher, B. / Sinning, I. / Kappes, B. / Tews, I.
External linksStructure / PubMed:22244765
MethodsX-ray diffraction
Resolution2.42 - 3.61 Å
Structure data

PDB-4ads:
Crystal structure of plasmodial PLP synthase complex
Method: X-RAY DIFFRACTION / Resolution: 3.61 Å

PDB-4adt:
Crystal structure of plasmodial PLP synthase
Method: X-RAY DIFFRACTION / Resolution: 2.42 Å

PDB-4adu:
Crystal structure of plasmodial PLP synthase with bound R5P intermediate
Method: X-RAY DIFFRACTION / Resolution: 2.44 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-R5P:
RIBOSE-5-PHOSPHATE

Source
  • plasmodium berghei (eukaryote)
  • plasmodium falciparum (malaria parasite P. falciparum)
KeywordsTRANSFERASE/TRANSFERASE / TRANSFERASE-TRANSFERASE COMPLEX / PYRIDOXAL 5-PHOSPHATE BIOSYNTHESIS / TRANSFERASE / SYNTHASE

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