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TitleExpression of a soluble form of iodotyrosine deiodinase for active site characterization by engineering the native membrane protein from Mus musculus.
Journal, issue, pagesProtein Sci., Vol. 21, Page 351-361, Year 2012
Publish dateSep 2, 2011 (structure data deposition date)
AuthorsBuss, J.M. / McTamney, P.M. / Rokita, S.E.
External linksProtein Sci. / PubMed:22238141
MethodsX-ray diffraction
Resolution2.25 - 2.655 Å
Structure data

PDB-3tnz:
Crystal structure of Mus musculus iodotyrosine deiodinase (IYD) C217A, C239A bound to FMN and mono-iodotyrosine (MIT)
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-3to0:
Crystal structure of Mus musculus iodotyrosine deiodinase (IYD) C217A, C239A bound to FMN
Method: X-RAY DIFFRACTION / Resolution: 2.655 Å

Chemicals

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-IYR:
3-IODO-TYROSINE / hormone*YM

ChemComp-FLC:
CITRATE ANION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-PO4:
PHOSPHATE ION

ChemComp-ACT:
ACETATE ION

Source
  • mus musculus (house mouse)
KeywordsOXIDOREDUCTASE / FLAVOPROTEIN / MEMBRANE / TRANSMEMBRANE / DEHALOGENASE / IODIDE SALVAGE / FMN / MONO-IODOTYROSINE / MIT / NADP

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