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Structure paper

TitleThe molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator.
Journal, issue, pagesNucleic Acids Res., Vol. 40, Page 3913-3928, Year 2012
Publish dateNov 15, 2011 (structure data deposition date)
AuthorsJungmichel, S. / Clapperton, J.A. / Lloyd, J. / Hari, F.J. / Spycher, C. / Pavic, L. / Li, J. / Haire, L.F. / Bonalli, M. / Larsen, D.H. ...Jungmichel, S. / Clapperton, J.A. / Lloyd, J. / Hari, F.J. / Spycher, C. / Pavic, L. / Li, J. / Haire, L.F. / Bonalli, M. / Larsen, D.H. / Lukas, C. / Lukas, J. / MacMillan, D. / Nielsen, M.L. / Stucki, M. / Smerdon, S.J.
External linksNucleic Acids Res. / PubMed:22234878
MethodsX-ray diffraction
Resolution1.8 - 2.3 Å
Structure data

PDB-3un0:
Crystal Structure of MDC1 FHA Domain
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-3uot:
Crystal Structure of MDC1 FHA Domain in Complex with a Phosphorylated Peptide from the MDC1 N-terminus
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCELL CYCLE / FHA domain / DNA-damage / MDC1 dimerization

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