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Structure paper

TitleStructural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68.
Journal, issue, pagesBiochemistry, Year 2012
Publish dateDec 28, 2011 (structure data deposition date)
AuthorsWu, H.H. / Wu, P.Y. / Huang, K.F. / Kao, Y.Y. / Tsai, M.D.
External linksBiochemistry / PubMed:22211259
MethodsX-ray diffraction
Resolution1.54 - 1.74 Å
Structure data

PDB-3va1:
Crystal structure of the mammalian MDC1 FHA domain
Method: X-RAY DIFFRACTION / Resolution: 1.74 Å

PDB-3va4:
Crystal structure of the mammalian MDC1 FHA domain complexed with CHK2 pThr68 peptide
Method: X-RAY DIFFRACTION / Resolution: 1.54 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsCELL CYCLE / FHA domain / DNA-damage / MDC1 dimerization / CHK2 and MDC1 dimerization

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