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-Structure paper
Title | Structural Basis of C-terminal beta-Amyloid Peptide Binding by the Antibody Ponezumab for the Treatment of Alzheimer's Disease |
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Journal, issue, pages | J. Mol. Biol., Vol. 421, Page 525-536, Year 2012 |
Publish date | Sep 29, 2011 (structure data deposition date) |
Authors | La Porte, S.L. / Bollini, S.S. / Lanz, T.A. / Abdiche, Y.N. / Rusnak, A.S. / Ho, W.H. / Kobayashi, D. / Harrabi, O. / Pappas, D. / Mina, E.W. ...La Porte, S.L. / Bollini, S.S. / Lanz, T.A. / Abdiche, Y.N. / Rusnak, A.S. / Ho, W.H. / Kobayashi, D. / Harrabi, O. / Pappas, D. / Mina, E.W. / Milici, A.J. / Kawabe, T.T. / Bales, K. / Lin, J.C. / Pons, J. |
External links | J. Mol. Biol. / PubMed:22197375 |
Methods | X-ray diffraction |
Resolution | 2.5 Å |
Structure data | PDB-3u0t: |
Chemicals | ChemComp-HOH: |
Source |
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Keywords | IMMUNE SYSTEM / antibody Fab / immunotherapeutic |