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Structure paper

TitleA structural basis for varied alpha-beta TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule.
Journal, issue, pagesJ. Immunol., Vol. 188, Page 311-321, Year 2012
Publish dateJun 22, 2011 (structure data deposition date)
AuthorsGras, S. / Wilmann, P.G. / Chen, Z. / Halim, H. / Liu, Y.C. / Kjer-Nielsen, L. / Purcell, A.W. / Burrows, S.R. / McCluskey, J. / Rossjohn, J.
External linksJ. Immunol. / PubMed:22140258
MethodsX-ray diffraction
Resolution1.6 - 3.1 Å
Structure data

PDB-3sjv:
Crystal structure of the RL42 TCR in complex with HLA-B8-FLR
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-3skm:
Crystal structure of the HLA-B8FLRGRAYVL, mutant G8V of the FLR peptide
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-3skn:
Crystal structure of the RL42 TCR unliganded
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-3sko:
Crystal structure of the HLA-B8-A66-FLR, mutant A66 of the HLA B8
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-NA:
Unknown entry

Source
  • homo sapiens (human)
  • human herpesvirus 4 (Epstein-Barr virus)
KeywordsIMMUNE SYSTEM / T cell / T cell receptor / antigen presentation

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