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TitleUnusual carbon fixation gives rise to diverse polyketide extender units.
Journal, issue, pagesNat. Chem. Biol., Vol. 8, Page 117-124, Year 2011
Publish dateSep 12, 2011 (structure data deposition date)
AuthorsQuade, N. / Huo, L. / Rachid, S. / Heinz, D.W. / Muller, R.
External linksNat. Chem. Biol. / PubMed:22138621
MethodsX-ray diffraction
Resolution1.9 - 2.25 Å
Structure data

PDB-4a0s:
STRUCTURE OF THE 2-OCTENOYL-COA CARBOXYLASE REDUCTASE CINF IN COMPLEX WITH NADP AND 2-OCTENOYL-COA
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4a10:
Apo-structure of 2-octenoyl-CoA carboxylase reductase CinF from streptomyces sp.
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-CO8:
OCTANOYL-COENZYME A

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-HOH:
WATER

Source
  • streptomyces sp. (bacteria)
KeywordsOXIDOREDUCTASE / TRANSFERASE / CINNABARAMIDE PKS BIOSYNTHESIS / CCR / PKS BUILDING BLOCKS / ROSSMANN FOLD

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