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TitleCrystal structure of thrombin in complex with s-variegin: insights of a novel mechanism of inhibition and design of tunable thrombin inhibitors
Journal, issue, pagesPlos One, Vol. 6, Page e26367-e26367, Year 2011
Publish dateJul 20, 2011 (structure data deposition date)
AuthorsKoh, C.Y. / Kumar, S. / Kazimirova, M. / Nuttall, P.A. / Radhakrishnan, U.P. / Kim, S. / Jagadeeswaran, P. / Imamura, T. / Mizuguchi, J. / Iwanaga, S. ...Koh, C.Y. / Kumar, S. / Kazimirova, M. / Nuttall, P.A. / Radhakrishnan, U.P. / Kim, S. / Jagadeeswaran, P. / Imamura, T. / Mizuguchi, J. / Iwanaga, S. / Swaminathan, K. / Kini, R.M.
External linksPlos One / PubMed:22053189
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-3b23:
Crystal structure of thrombin-variegin complex: Insights of a novel mechanism of inhibition and design of tunable thrombin inhibitors
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • amblyomma variegatum (tropical bont tick)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / HYDROLASE-HYDROLASE INHIBITOR complex

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