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TitleHuman mitochondrial transcription factor A induces a U-turn structure in the light strand promoter.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 18, Page 1281-1289, Year 2011
Publish dateSep 9, 2011 (structure data deposition date)
AuthorsRubio-Cosials, A. / Sidow, J.F. / Jimenez-Menendez, N. / Fernandez-Millan, P. / Montoya, J. / Jacobs, H.T. / Coll, M. / Bernado, P. / Sola, M.
External linksNat. Struct. Mol. Biol. / PubMed:22037172
MethodsX-ray diffraction
Resolution2.45 Å
Structure data

PDB-3tq6:
Crystal structure of human mitochondrial transcription factor A, TFAM or mtTFA, bound to the light strand promoter LSP
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

Chemicals

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

ChemComp-PO4:
PHOSPHATE ION

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION/DNA / Transcription / Transcription regulation / Mitochondrion / DNA-binding / HMGB-UBF_HMG-box / minor groove / tandem HMG boxes / TRANSCRIPTION-DNA complex / mitochondrial nucleoid / light-strand mitochondrial promoter / LSP

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