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TitleStructural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis.
Journal, issue, pagesBmc Struct. Biol., Vol. 11, Page 39-39, Year 2011
Publish dateJan 17, 2011 (structure data deposition date)
AuthorsEdwards, T.E. / Abramov, A.B. / Smith, E.R. / Baydo, R.O. / Leonard, J.T. / Leibly, D.J. / Thompkins, K.B. / Clifton, M.C. / Gardberg, A.S. / Staker, B.L. ...Edwards, T.E. / Abramov, A.B. / Smith, E.R. / Baydo, R.O. / Leonard, J.T. / Leibly, D.J. / Thompkins, K.B. / Clifton, M.C. / Gardberg, A.S. / Staker, B.L. / Van Voorhis, W.C. / Myler, P.J. / Stewart, L.J.
External linksBmc Struct. Biol. / PubMed:21995815
MethodsX-ray diffraction
Resolution1.7 - 1.9 Å
Structure data

PDB-3qd5:
Crystal structure of a putative ribose-5-phosphate isomerase from Coccidioides immitis solved by combined iodide ion SAD and MR
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-3sdw:
Crystal structure of a ribose-5-phosphate isomerase B RpiB from Coccidioides immitis bound to phosphate
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-3sgw:
Crystal structure of ribose-5-phosphate isomerase B RpiB from Coccidioides immitis semi-covalently bound to malonic acid
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL / Ethylene glycol

ChemComp-IOD:
IODIDE ION / Iodide

ChemComp-HOH:
WATER / Water

ChemComp-PO4:
PHOSPHATE ION / Phosphate

ChemComp-CL:
Unknown entry / Chloride

ChemComp-MLA:
MALONIC ACID / Malonic acid

Source
  • coccidioides immitis (fungus)
KeywordsISOMERASE / Structural Genomics / Seattle Structural Genomics Center for Infectious Disease / SSGCID / Coccidioidomycosis / putative uncharacterized protein / hypothetical protein / ribose-5-phosphate isomerase / iodide ion / ribose-5-phosphate / RpiB / Valley Fever / pathogenic fungus / dust-borne pathogen / nucleotide and co-factor biogenesis / pentose phosphate pathway / ISOMERASE/ISOMERASE INHIBITOR / Coccidioidomycosis immitis / iodoacetic acid / covalent inhibitor / ribulose-5-phosphate / ISOMERASE-ISOMERASE INHIBITOR complex

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