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Structure paper

TitleCrystal Structure of Reduced and of Oxidized Peroxiredoxin IV Enzyme Reveals a Stable Oxidized Decamer and a Non-disulfide-bonded Intermediate in the Catalytic Cycle.
Journal, issue, pagesJ. Biol. Chem., Vol. 286, Page 42257-42266, Year 2011
Publish dateAug 24, 2011 (structure data deposition date)
AuthorsCao, Z. / Tavender, T.J. / Roszak, A.W. / Cogdell, R.J. / Bulleid, N.J.
External linksJ. Biol. Chem. / PubMed:21994946
MethodsX-ray diffraction
Resolution1.91 - 2.38 Å
Structure data

PDB-3tjb:
Crystal structure of wild-type human peroxiredoxin IV
Method: X-RAY DIFFRACTION / Resolution: 2.38 Å

PDB-3tjf:
Crystal Structure of human peroxiredoxin IV C51A mutant in reduced form
Method: X-RAY DIFFRACTION / Resolution: 2.04 Å

PDB-3tjg:
Crystal Structure of human peroxiredoxin IV C51A mutant in oxidized form
Method: X-RAY DIFFRACTION / Resolution: 2.24 Å

PDB-3tjj:
Crystal structure of human peroxiredoxin IV C245A mutant in sulfenylated form
Method: X-RAY DIFFRACTION / Resolution: 1.91 Å

PDB-3tjk:
Crystal Structure of human peroxiredoxin IV C245A mutant in reduced form
Method: X-RAY DIFFRACTION / Resolution: 2.09 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / thioredoxin fold / sulfenylation / endoplasmic reticulum

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