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TitleConformation-sensing antibodies stabilize the oxidized form of PTP1B and inhibit its phosphatase activity.
Journal, issue, pagesCell, Vol. 147, Page 185-198, Year 2011
Publish dateJul 22, 2011 (structure data deposition date)
AuthorsHaque, A. / Andersen, J.N. / Salmeen, A. / Barford, D. / Tonks, N.K.
External linksCell / PubMed:21962515
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-3zv2:
Human protein-tyrosine phosphatase 1b C215A, S216A mutant
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Source
  • homo sapiens (human)
KeywordsHYDROLASE / PHOSPHORYLATION

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