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TitleInsights into the Molecular Activation Mechanism of the RhoA-specific Guanine Nucleotide Exchange Factor, PDZRhoGEF.
Journal, issue, pagesJ. Biol. Chem., Vol. 286, Page 35163-35175, Year 2011
Publish dateJul 19, 2011 (structure data deposition date)
AuthorsBielnicki, J.A. / Shkumatov, A.V. / Derewenda, U. / Somlyo, A.V. / Svergun, D.I. / Derewenda, Z.S.
External linksJ. Biol. Chem. / PubMed:21816819
MethodsX-ray diffraction
Resolution2.84 Å
Structure data

PDB-3t06:
Crystal Structure of the DH/PH fragment of PDZRHOGEF with N-terminal regulatory elements in complex with Human RhoA
Method: X-RAY DIFFRACTION / Resolution: 2.84 Å

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / DH-PH RhoA complex / PDZRhoGEF / GUANINE NUCLEOTIDE EXCHANGE FACTOR / RhoA

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