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TitleStructural basis for matrix metalloproteinase-2 (MMP-2)-selective inhibitory action of {beta}-amyloid precursor protein-derived inhibitor
Journal, issue, pagesJ. Biol. Chem., Year 2011
Publish dateMay 17, 2011 (structure data deposition date)
AuthorsHashimoto, H. / Takeuchi, T. / Komatsu, K. / Miyazaki, K. / Sato, M. / Higashi, S.
External linksJ. Biol. Chem. / PubMed:21813640
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-3ayu:
Crystal structure of MMP-2 active site mutant in complex with APP-drived decapeptide inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / protease / HYDROLASE-HYDROLASE INHIBITOR complex

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