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Structure paper

TitleStructural basis for iloprost as a dual peroxisome proliferator-activated receptor alpha/delta agonist.
Journal, issue, pagesJ. Biol. Chem., Vol. 286, Page 31473-31479, Year 2011
Publish dateJul 1, 2011 (structure data deposition date)
AuthorsJin, L. / Lin, S. / Rong, H. / Zheng, S. / Jin, S. / Wang, R. / Li, Y.
External linksJ. Biol. Chem. / PubMed:21775429
MethodsX-ray diffraction
Resolution2.21 - 2.3 Å
Structure data

PDB-3sp6:
Structural basis for iloprost as a dual PPARalpha/delta agonist
Method: X-RAY DIFFRACTION / Resolution: 2.21 Å

PDB-3sp9:
Structural basis for iloprost as a dual PPARalpha/delta agonist
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-IL2:
(5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S,4R)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]hexahydropentalen-2(1H)-ylidene]pentanoic acid

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / PPAR LBD / nuclear receptor fold / ligand binding / gene transcription / nuclear receptor LBD / drug binding

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