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Structure paper

TitleStructural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 108, Page 11860-11865, Year 2011
Publish dateApr 8, 2011 (structure data deposition date)
AuthorsXiao, J. / Engel, J.L. / Zhang, J. / Chen, M.J. / Manning, G. / Dixon, J.E.
External linksProc. Natl. Acad. Sci. USA / PubMed:21730175
MethodsX-ray diffraction
Resolution1.928 - 2.05 Å
Structure data

PDB-3rgo:
Crystal Structure of PTPMT1
Method: X-RAY DIFFRACTION / Resolution: 1.928 Å

PDB-3rgq:
Crystal Structure of PTPMT1 in complex with PI(5)P
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-5P5:
(2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,4,6-tetrahydroxy-5-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dibutanoate

Source
  • mus musculus (house mouse)
KeywordsHYDROLASE / phosphatidylglycerol phosphate (PGP) phosphatase

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