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Structure paper

TitleStudies on the Reaction of Nitric Oxide with the Hypoxia-Inducible Factor Prolyl Hydroxylase Domain 2 (Egln1)
Journal, issue, pagesJ. Mol. Biol., Vol. 410, Page 268-279, Year 2011
Publish dateDec 18, 2010 (structure data deposition date)
AuthorsChowdhury, R. / Flashman, E. / Mecinovic, J. / Kramer, H.B. / Kessler, B.M. / Frapart, Y.M. / Boucher, J.-L. / Clifton, I.J. / McDonough, M.A. / Schofield, C.J.
External linksJ. Mol. Biol. / PubMed:21601578
MethodsX-ray diffraction
Resolution2 - 2.01 Å
Structure data

PDB-2y33:
S-nitrosylated PHD2 (GSNO soaked) in complex with Zn(II) and UN9
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2y34:
S-nitrosylated PHD2 (NO exposed) in complex with Fe(II) and UN9
Method: X-RAY DIFFRACTION / Resolution: 2.01 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-UN9:
N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE

ChemComp-HOH:
WATER

ChemComp-FE2:
Unknown entry

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / NON-HEME / TRANSCRIPTION AND EPIGENETIC REGULATION

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