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| Title | An anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loop. |
|---|---|
| Journal, issue, pages | Protein Sci., Vol. 20, Page 1196-1207, Year 2011 |
| Publish date | Mar 2, 2011 (structure data deposition date) |
Authors | Fanning, S.W. / Horn, J.R. |
External links | Protein Sci. / PubMed:21557375 |
| Methods | X-ray diffraction |
| Resolution | 1.7 - 2.5 Å |
| Structure data | ![]() PDB-3qxt: ![]() PDB-3qxu: ![]() PDB-3qxv: ![]() PDB-3qxw: |
| Chemicals | ![]() ChemComp-MTX: ![]() ChemComp-NA: ![]() ChemComp-HOH: ![]() ChemComp-FMT: ![]() ChemComp-SO4: |
| Source |
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Keywords | IMMUNE SYSTEM / Camelid Single Domain Antibody / Heavy Chain Only / VHH / Antibody / Anti-Hapten Antibody / CDR / Hapten Binding / Small Molecule Sensing / Ligand Binding / Low Molecular Weight Compound / Methotrexate / CDR1 / CDR4 |
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