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Structure paper

TitleStructural characterization of the mitomycin 7-O-methyltransferase.
Journal, issue, pagesProteins, Vol. 79, Page 2181-2188, Year 2011
Publish dateApr 1, 2009 (structure data deposition date)
AuthorsSingh, S. / Chang, A. / Goff, R.D. / Bingman, C.A. / Gruschow, S. / Sherman, D.H. / Phillips, G.N. / Thorson, J.S.
External linksProteins / PubMed:21538548
MethodsX-ray diffraction
Resolution1.91 - 2.3 Å
Structure data

PDB-3gwz:
Structure of the Mitomycin 7-O-methyltransferase MmcR
Method: X-RAY DIFFRACTION / Resolution: 1.91 Å

PDB-3gxo:
Structure of the Mitomycin 7-O-methyltransferase MmcR with bound Mitomycin A
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-HOH:
WATER

ChemComp-MQA:
[(1aS,8S,8aR,8bS)-6,8a-dimethoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate

Source
  • streptomyces lavendulae (bacteria)
KeywordsTRANSFERASE / Methyltransferase / Mitomycin / MmcR / S-adenosyl methionine

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