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Structure paper

TitleThe Structural Basis of Agonist Induced Activation in Constitutively Active Rhodopsin
Journal, issue, pagesNature, Vol. 471, Page 656-, Year 2011
Publish dateFeb 22, 2010 (structure data deposition date)
AuthorsStandfuss, J. / Edwards, P.C. / Dantona, A. / Fransen, M. / Xie, G. / Oprian, D.D. / Schertler, G.F.X.
External linksNature / PubMed:21389983
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-2x72:
CRYSTAL STRUCTURE OF THE CONSTITUTIVELY ACTIVE E113Q,D2C,D282C RHODOPSIN MUTANT WITH BOUND GALPHACT PEPTIDE.
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-PEF:
DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE / phospholipid*YM

ChemComp-BOG:
octyl beta-D-glucopyranoside / detergent*YM

ChemComp-PLM:
PALMITIC ACID

ChemComp-RET:
RETINAL

ChemComp-LPP:
2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE / phospholipid*YM

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • bos taurus (domestic cattle)
KeywordsSIGNALING PROTEIN / CHROMOPHORE / LIPOPROTEIN / GLYCOPROTEIN / TRANSMEMBRANE / RETINAL PROTEIN / G-PROTEIN COUPLED RECEPTOR / SENSORY TRANSDUCTION / PHOTORECEPTOR PROTEIN

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