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TitleStructural insights into the extracellular assembly of the hematopoietic Flt3 signaling complex.
Journal, issue, pagesBlood, Vol. 118, Page 60-68, Year 2011
Publish dateFeb 19, 2011 (structure data deposition date)
AuthorsVerstraete, K. / Vandriessche, G. / Januar, M. / Elegheert, J. / Shkumatov, A.V. / Desfosses, A. / Van Craenenbroeck, K. / Svergun, D.I. / Gutsche, I. / Vergauwen, B. / Savvides, S.N.
External linksBlood / PubMed:21389326
MethodsX-ray diffraction
Resolution4.3 - 7.8 Å
Structure data

PDB-3qs7:
Crystal structure of a human Flt3 ligand-receptor ternary complex
Method: X-RAY DIFFRACTION / Resolution: 4.3 Å

PDB-3qs9:
Crystal structure of a human Flt3 ligand-receptor ternary complex
Method: X-RAY DIFFRACTION / Resolution: 7.8 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
KeywordsCYTOKINE/SIGNALING PROTEIN / immunoglobulin-like domain / four-helical bundle cytokine / cytokine-receptor complex / extracellular complex / receptor tyrosine kinase / CYTOKINE-SIGNALING PROTEIN complex / hematopoietic cytokine-receptor complex / cell surface

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