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Structure paper

TitleAtomic Level Description of the Domain Closure in a Dimeric Enzyme: Thermus Thermophilus 3-Isopropylmalate Dehydrogenase.
Journal, issue, pagesMol. Biosyst., Vol. 7, Page 1646-, Year 2011
Publish dateJan 4, 2011 (structure data deposition date)
AuthorsGraczer, E. / Merli, A. / Singh, R.K. / Karuppasamy, M. / Zavodszky, P. / Weiss, M.S. / Vas, M.
External linksMol. Biosyst. / PubMed:21387033
MethodsX-ray diffraction
Resolution1.83 - 2.5 Å
Structure data

PDB-2y3z:
Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - apo enzyme
Method: X-RAY DIFFRACTION / Resolution: 1.83 Å

PDB-2y40:
Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - complex with Mn
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-2y41:
Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - complex with IPM and MN
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-2y42:
Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - complex with NADH and Mn
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-2PE:
NONAETHYLENE GLYCOL / precipitant*YM

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-MN:
Unknown entry

ChemComp-IPM:
3-ISOPROPYLMALIC ACID

ChemComp-BCN:
BICINE / pH buffer*YM

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

Source
  • thermus thermophilus (bacteria)
KeywordsOXIDOREDUCTASE / LEUB / LEUCINE BIOSYNTHESIS

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