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TitleStructural basis for recognition of urokinase-type plasminogen activator by plasminogen activator inhibitor-1.
Journal, issue, pagesJ. Biol. Chem., Vol. 286, Page 7027-7032, Year 2011
Publish dateOct 20, 2010 (structure data deposition date)
AuthorsLin, Z. / Jiang, L. / Yuan, C. / Jensen, J.K. / Zhang, X. / Luo, Z. / Furie, B.C. / Furie, B. / Andreasen, P.A. / Huang, M.
External linksJ. Biol. Chem. / PubMed:21199867
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-3pb1:
Crystal Structure of a Michaelis Complex between Plasminogen Activator Inhibitor-1 and Urokinase-type Plasminogen Activator
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
Keywordshydrolase Inhibitor/Hydrolase / PAI-1 / uPA / Michaelis complex / Structural Genomics / Structure 2 Function Project / S2F / hydrolase Inhibitor-Hydrolase complex

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