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Structure paper

TitleTRIM24 links a non-canonical histone signature to breast cancer.
Journal, issue, pagesNature, Vol. 468, Page 927-932, Year 2010
Publish dateJul 23, 2010 (structure data deposition date)
AuthorsTsai, W.W. / Wang, Z. / Yiu, T.T. / Akdemir, K.C. / Xia, W. / Winter, S. / Tsai, C.Y. / Shi, X. / Schwarzer, D. / Plunkett, W. ...Tsai, W.W. / Wang, Z. / Yiu, T.T. / Akdemir, K.C. / Xia, W. / Winter, S. / Tsai, C.Y. / Shi, X. / Schwarzer, D. / Plunkett, W. / Aronow, B. / Gozani, O. / Fischle, W. / Hung, M.C. / Patel, D.J. / Barton, M.C.
External linksNature / PubMed:21164480
MethodsX-ray diffraction
Resolution1.7 - 2 Å
Structure data

PDB-3o33:
Crystal structure of TRIM24 PHD-Bromo in the free state
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-3o34:
Crystal structure of TRIM24 PHD-Bromo complexed with H3(13-32)K23ac peptide
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-3o35:
Crystal structure of TRIM24 PHD-Bromo complexed with H3(23-31)K27ac peptide
Method: X-RAY DIFFRACTION / Resolution: 1.76 Å

PDB-3o36:
Crystal structure of TRIM24 PHD-Bromo complexed with H4(14-19)K16ac peptide
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-3o37:
Crystal structure of TRIM24 PHD-Bromo complexed with H3(1-10)K4 peptide
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-BTN:
BIOTIN

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / PHD finger / Bromodomain / TRIM24 / breast cancer / TRANSCRIPTION/protein binding / H3K23ac / TRANSCRIPTION-protein binding complex / H3K27 acetylation / H4K16 acetylation / unmodified H3K4

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