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TitleCrystal structure of the catalytic core of Saccharomyces cerevesiae histone demethylase Rph1: insights into the substrate specificity and catalytic mechanism
Journal, issue, pagesBiochem. J., Vol. 433, Page 295-302, Year 2011
Publish dateSep 2, 2010 (structure data deposition date)
AuthorsChang, Y. / Wu, J. / Tong, X.J. / Zhou, J.Q. / Ding, J.
External linksBiochem. J. / PubMed:21067515
MethodsX-ray diffraction
Resolution2.2 - 2.5 Å
Structure data

PDB-3opt:
Crystal structure of the Rph1 catalytic core with a-ketoglutarate
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-3opw:
Crystal Structure of the Rph1 catalytic core
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-AKG:
2-OXOGLUTARIC ACID

ChemComp-NI:
NICKEL (II) ION

ChemComp-HOH:
WATER

Source
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsOXIDOREDUCTASE / Rph1 / histone demethylase / catalytic core

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