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Structure paper

TitleStructural Basis for C-Kit Inhibition by the Suppressor of Cytokine Signaling 6 (Socs6) Ubiquitin Ligase.
Journal, issue, pagesJ. Biol. Chem., Vol. 286, Page 480-, Year 2011
Publish dateNov 30, 2007 (structure data deposition date)
AuthorsZadjali, F. / Pike, A.C.W. / Vesterlund, M. / Sun, J. / Wu, C. / Li, S.S. / Ronnstrand, L. / Knapp, S. / Bullock, A. / Flores-Morales, A.
External linksJ. Biol. Chem. / PubMed:21030588
MethodsX-ray diffraction
Resolution1.45 Å
Structure data

PDB-2vif:
Crystal structure of SOCS6 SH2 domain in complex with a c-KIT phosphopeptide
Method: X-RAY DIFFRACTION / Resolution: 1.45 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / GROWTH REGULATION / SIGNAL TRANSDUCTION INHIBITOR / KIT REGULATOR / PHOSPHOTYROSINE

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