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Structure paper

TitleStructural basis for glucose-6-phosphate activation of glycogen synthase.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 107, Page 17563-17568, Year 2010
Publish dateJun 2, 2010 (structure data deposition date)
AuthorsBaskaran, S. / Roach, P.J. / Depaoli-Roach, A.A. / Hurley, T.D.
External linksProc. Natl. Acad. Sci. USA / PubMed:20876143
MethodsX-ray diffraction
Resolution2.406 - 3.512 Å
Structure data

PDB-3naz:
Basal state form of Yeast Glycogen Synthase
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-3nb0:
Glucose-6-Phosphate activated form of Yeast Glycogen Synthase
Method: X-RAY DIFFRACTION / Resolution: 2.406 Å

PDB-3nch:
Yeast Glycogen Synthase (Gsy2p) Basal State Conformation
Method: X-RAY DIFFRACTION / Resolution: 2.88 Å

PDB-3o3c:
Glycogen synthase basal state UDP complex
Method: X-RAY DIFFRACTION / Resolution: 3.512 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-G6P:
6-O-phosphono-alpha-D-glucopyranose

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

ChemComp-UDP:
URIDINE-5'-DIPHOSPHATE / UDP*YM

Source
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsTRANSFERASE / Glycogen Synthase / Glucose-6-phosphate / Yeast / Allosteric activation

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