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TitleCharacterisation of a Novel Wdr5 Binding Site that Recruits Rbbp5 Through a Conserved Motif and Enhances Methylation of H3K4 by Mll1.
Journal, issue, pagesJ. Biol. Chem., Vol. 285, Page 32967-, Year 2010
Publish dateJul 19, 2010 (structure data deposition date)
AuthorsOdho, Z. / Southall, S.M. / Wilson, J.R.
External linksJ. Biol. Chem. / PubMed:20716525
MethodsX-ray diffraction
Resolution2.4 - 2.7 Å
Structure data

PDB-2xl2:
WDR5 IN COMPLEX WITH AN RBBP5 PEPTIDE RECRUITED TO NOVEL SITE
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-2xl3:
WDR5 IN COMPLEX WITH AN RBBP5 PEPTIDE AND HISTONE H3 PEPTIDE
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsTRANSCRIPTION / MLL COMPLEX / H3K4 METHYLATION / WD-40 BETA-PROPELLER

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