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TitleCrystal Structures of Phd-Doc, HigA, and YeeU Establish Multiple Evolutionary Links between Microbial Growth-Regulating Toxin-Antitoxin Systems.
Journal, issue, pagesStructure, Vol. 18, Page 996-1010, Year 2010
Publish dateMay 18, 2006 (structure data deposition date)
AuthorsArbing, M.A. / Handelman, S.K. / Kuzin, A.P. / Verdon, G. / Wang, C. / Su, M. / Rothenbacher, F.P. / Abashidze, M. / Liu, M. / Hurley, J.M. ...Arbing, M.A. / Handelman, S.K. / Kuzin, A.P. / Verdon, G. / Wang, C. / Su, M. / Rothenbacher, F.P. / Abashidze, M. / Liu, M. / Hurley, J.M. / Xiao, R. / Acton, T. / Inouye, M. / Montelione, G.T. / Woychik, N.A. / Hunt, J.F.
External linksStructure / PubMed:20696400
MethodsX-ray diffraction
Resolution1.5 - 2.71 Å
Structure data

PDB-2h28:
Crystal structure of YeeU from E. coli. Northeast Structural Genomics target ER304
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-2ict:
Crystal structure of the bacterial antitoxin HigA from Escherichia coli at pH 8.5. Northeast Structural Genomics TARGET ER390.
Method: X-RAY DIFFRACTION / Resolution: 1.63 Å

PDB-2inw:
Crystal structure of Q83JN9 from Shigella flexneri at high resolution. Northeast Structural Genomics Consortium target SfR137.
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-3kh2:
Crystal structure of the P1 bacteriophage Doc toxin (F68S) in complex with the Phd antitoxin (L17M/V39A). Northeast Structural Genomics targets ER385-ER386
Method: X-RAY DIFFRACTION / Resolution: 2.71 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HED:
2-HYDROXYETHYL DISULFIDE

Source
  • escherichia coli (E. coli)
  • shigella flexneri (bacteria)
  • bacteriophage p1 (virus)
KeywordsSTRUCTURAL GENOMICS / UNKNOWN FUNCTION / ER304 / E. coli / PSI-2 / Protein Structure Initiative / Northeast Structural Genomics Consortium / NESG / DNA BINDING PROTEIN / helix-turn-helix / Q83JN9 X-Ray NESG SfR137 / TOXIN / antitoxin / NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG)

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