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TitleStructural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Journal, issue, pagesStructure, Vol. 18, Page 913-922, Year 2010
Publish dateApr 12, 2010 (structure data deposition date)
AuthorsZheng, J. / Taylor, C.A. / Piasecki, S.K. / Keatinge-Clay, A.T.
External linksStructure / PubMed:20696392
MethodsX-ray diffraction
Resolution1.36 - 1.6 Å
Structure data

PDB-3mjc:
Structure of A-type Ketoreductases from Modular Polyketide Synthase
Method: X-RAY DIFFRACTION / Resolution: 1.48 Å

PDB-3mje:
Structure of A-type Ketoreductases from Modular Polyketide Synthase
Method: X-RAY DIFFRACTION / Resolution: 1.36 Å

PDB-3mjs:
Structure of A-type Ketoreductases from Modular Polyketide Synthase
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-3mjt:
Structure of A-type Ketoreductases from Modular Polyketide Synthase
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-3mjv:
Structure of A-type Ketoreductases from Modular Polyketide Synthase
Method: X-RAY DIFFRACTION / Resolution: 1.46 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-NDP:
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-LMR:
(2S)-2-hydroxybutanedioic acid

ChemComp-MLT:
D-MALATE

Source
  • streptomyces nodosus (bacteria)
KeywordsOXIDOREDUCTASE / Rossmann fold

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