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TitleLoop-sheet mechanism of serpin polymerization tested by reactive center loop mutations
Journal, issue, pagesJ. Biol. Chem., Vol. 285, Page 30752-30758, Year 2010
Publish dateJun 7, 2010 (structure data deposition date)
AuthorsYamasaki, M. / Sendall, T.J. / Harris, L.E. / Lewis, G.M.W. / Huntington, J.A.
External linksJ. Biol. Chem. / PubMed:20667823
MethodsX-ray diffraction
Resolution1.5 - 2.7 Å
Structure data

PDB-3ndd:
Cleaved antitrypsin with P10 Pro, and P9-P6 Asp
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-3ndf:
Cleaved antitrypsin with P8-P6 Asp
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE INHIBITOR / serpin

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