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Structure paper

TitleStructural basis for the transcriptional regulation of membrane lipid homeostasis.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 17, Page 971-975, Year 2010
Publish dateFeb 12, 2010 (structure data deposition date)
AuthorsMiller, D.J. / Zhang, Y.M. / Subramanian, C. / Rock, C.O. / White, S.W.
External linksNat. Struct. Mol. Biol. / PubMed:20639888
MethodsX-ray diffraction
Resolution2.3 - 2.66 Å
Structure data

PDB-3lsj:
Crystal structure of DesT in complex with palmitoyl-CoA
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-3lsp:
Crystal Structure of DesT bound to desCB promoter and oleoyl-CoA
Method: X-RAY DIFFRACTION / Resolution: 2.66 Å

PDB-3lsr:
Crystal structure of DesT in complex with duplex DNA
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

Chemicals

ChemComp-PLM:
PALMITIC ACID

ChemComp-COA:
COENZYME A

ChemComp-HOH:
WATER

ChemComp-OLA:
OLEIC ACID

ChemComp-SO4:
SULFATE ION

Source
  • pseudomonas aeruginosa (bacteria)
KeywordsTRANSCRIPTION / Transcriptional Repressor / DesT / TetR family / DNA-binding / Transcription regulation / TRANSCRIPTION/DNA / DesT-DNA complex / TRANSCRIPTION-DNA complex

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