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Structure paper

TitleThe adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes.
Journal, issue, pagesProteins, Vol. 10, Page 50-69, Year 1991
Publish dateApr 23, 2001 (structure data deposition date)
AuthorsNoble, M.E. / Wierenga, R.K. / Lambeir, A.M. / Opperdoes, F.R. / Thunnissen, A.M. / Kalk, K.H. / Groendijk, H. / Hol, W.G.
External linksProteins / PubMed:2062828
MethodsX-ray diffraction
Resolution2.2 - 2.6 Å
Structure data

PDB-1iig:
STRUCTURE OF TRYPANOSOMA BRUCEI BRUCEI TRIOSEPHOSPHATE ISOMERASE COMPLEXED WITH 3-PHOSPHONOPROPIONATE
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-1iih:
STRUCTURE OF TRYPANOSOMA BRUCEI BRUCEI TRIOSEPHOSPHATE ISOMERASE COMPLEXED WITH 3-PHOSPHOGLYCERATE
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-6tim:
THE ADAPTABILITY OF THE ACTIVE SITE OF TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE AS OBSERVED IN THE CRYSTAL STRUCTURES OF THREE DIFFERENT COMPLEXES
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-3PP:
3-PHOSPHONOPROPANOIC ACID

ChemComp-HOH:
WATER

ChemComp-3PG:
3-PHOSPHOGLYCERIC ACID

ChemComp-G3P:
SN-GLYCEROL-3-PHOSPHATE

Source
  • trypanosoma brucei brucei (eukaryote)
KeywordsISOMERASE / TIM ligand complex / ISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE)

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