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-Structure paper
Title | Structurally Designed trans-2-Phenylcyclopropylamine Derivatives Potently Inhibit Histone Demethylase LSD1/KDM1 |
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Journal, issue, pages | Biochemistry, Vol. 49, Page 6494-6503, Year 2010 |
Publish date | Dec 21, 2009 (structure data deposition date) |
Authors | Mimasu, S. / Umezawa, N. / Sato, S. / Higuchi, T. / Umehara, T. / Yokoyama, S. |
External links | Biochemistry / PubMed:20568732 |
Methods | X-ray diffraction |
Resolution | 3.1 - 3.2 Å |
Structure data | PDB-3abt: PDB-3abu: |
Chemicals | ChemComp-2PF: ChemComp-12F: |
Source |
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Keywords | OXIDOREDUCTASE / Amine Oxidase / Histone demethylase / Tower domain / H3K4 / Structural Genomics / RIKEN Structural Genomics/Proteomics Initiative / RSGI / Chromatin regulator / Developmental protein / FAD / Nucleus / Phosphoprotein / Repressor / Transcription / Transcription regulation / NPPSFA / National Project on Protein Structural and Functional Analyses |