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Structure paper

TitleStructural Basis for Par-4 Recognition by the Spry Domain-and Socs Box-Containing Proteins Spsb1, Spsb2, and Spsb4.
Journal, issue, pagesJ. Mol. Biol., Vol. 401, Page 389-, Year 2010
Publish dateAug 22, 2008 (structure data deposition date)
AuthorsFilippakopoulos, P. / Low, A. / Sharpe, T.D. / Uppenberg, J. / Yao, S. / Kuang, Z. / Savitsky, P. / Lewis, R.S. / Nicholson, S.E. / Norton, R.S. / Bullock, A.
External linksJ. Mol. Biol. / PubMed:20561531
MethodsX-ray diffraction
Resolution1.79 - 2.2 Å
Structure data

PDB-2jk9:
The structure of splA-ryanodine receptor domain and SOCS box containing 1 in complex with a PAR-4 peptide
Method: X-RAY DIFFRACTION / Resolution: 1.79 Å

PDB-2v24:
Structure of the human SPRY domain-containing SOCS box protein SSB-4
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-3emw:
Crystal Structure of human splA/ryanodine receptor domain and SOCS box containing 2 (SPSB2) in complex with a 20-residue VASA peptide
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-3f2o:
Crystal Structure of human splA/ryanodine receptor domain and SOCS box containing 1 (SPSB1) in complex with a 20-residue VASA peptide
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-NI:
NICKEL (II) ION

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • homo sapiens (human)
KeywordsAPOPTOSIS / TRANSCRIPTION REGULATION / TRANSCRIPTION / PROTEIN BINDING / PROTEIN-BINDING / Apoptosis nucleus / UBL conjugation pathwayc / CL transcription regulation / Phosphoprotein / Ubl conjugation pathway / Structural Genomics / Structural Genomics Consortium / SGC / APOPTOSIS/HYDROLASE / nucleus / ATP-binding / Developmental protein / Differentiation / Helicase / Hydrolase / Nucleotide-binding / Oogenesis / APOPTOSIS-HYDROLASE COMPLEX

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