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-Structure paper
Title | Mechanism of Inhibition of Novel Tryptophan Hydroxylase Inhibitors Revealed by Co-crystal Structures and Kinetic Analysis. |
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Journal, issue, pages | Curr Chem Genomics, Vol. 4, Page 19-26, Year 2010 |
Publish date | May 11, 2009 (structure data deposition date) |
![]() | Cianchetta, G. / Stouch, T. / Yu, W. / Shi, Z.C. / Tari, L.W. / Swanson, R.V. / Hunter, M.J. / Hoffman, I.D. / Liu, Q. |
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Methods | X-ray diffraction |
Resolution | 1.85 - 1.92 Å |
Structure data | ![]() PDB-3hf8: ![]() PDB-3hfb: |
Chemicals | ![]() ChemComp-FE: ![]() ChemComp-ML0: ![]() ChemComp-HOH: ![]() ChemComp-ML4: |
Source |
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![]() | OXIDOREDUCTASE / TRYOPTOPHAN HYDROXYLASE TYPE 1 / Iron / Metal-binding / Monooxygenase / Phosphoprotein / Serotonin biosynthesis / Tryptophan Hydroxylase type 1 |