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Structure paper

TitleStructural basis for NADH/NAD+ redox sensing by a Rex family repressor.
Journal, issue, pagesMol. Cell, Vol. 38, Page 563-575, Year 2010
Publish dateAug 6, 2009 (structure data deposition date)
AuthorsMcLaughlin, K.J. / Strain-Damerell, C.M. / Xie, K. / Brekasis, D. / Soares, A.S. / Paget, M.S. / Kielkopf, C.L.
External linksMol. Cell / PubMed:20513431
MethodsX-ray diffraction
Resolution2.26 - 2.49 Å
Structure data

PDB-3ikt:
Crystal structure of a Rex-family repressor/DNA/NAD+ complex from Thermus aquaticus
Method: X-RAY DIFFRACTION / Resolution: 2.26 Å

PDB-3ikv:
Crystal structure of a Rex-family repressor R90D mutant from Thermus aquaticus
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-3il2:
Crystal structure of a Rex-family repressor R90D mutant/DNA complex from Thermus aquaticus
Method: X-RAY DIFFRACTION / Resolution: 2.49 Å

Chemicals

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-HOH:
WATER

ChemComp-CA:
Unknown entry

Source
  • thermus thermophilus hb27 (bacteria)
KeywordsDNA BINDING PROTEIN/DNA / redox-sensing / winged helix / Rossmann fold / Nicotinamide Adenine Dinucleotide / NAD / Rex / Thermus aquaticus / DNA BINDING PROTEIN / Cytoplasm / DNA-binding / Repressor / Transcription / Transcription regulation / DNA BINDING PROTEIN-DNA COMPLEX / Mutant

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