Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Design of selective, ATP-competitive inhibitors of Akt.
Journal, issue, pages	J. Med. Chem., Vol. 53, Page 4615-4622, Year 2010
Publish date	May 3, 2010 (structure data deposition date)
Authors	Freeman-Cook, K.D. / Autry, C. / Borzillo, G. / Gordon, D. / Barbacci-Tobin, E. / Bernardo, V. / Briere, D. / Clark, T. / Corbett, M. / Jakubczak, J. ...Freeman-Cook, K.D. / Autry, C. / Borzillo, G. / Gordon, D. / Barbacci-Tobin, E. / Bernardo, V. / Briere, D. / Clark, T. / Corbett, M. / Jakubczak, J. / Kakar, S. / Knauth, E. / Lippa, B. / Luzzio, M.J. / Mansour, M. / Martinelli, G. / Marx, M. / Nelson, K. / Pandit, J. / Rajamohan, F. / Robinson, S. / Subramanyam, C. / Wei, L. / Wythes, M. / Morris, J.
External links	J. Med. Chem. / PubMed:20481595
Methods	X-ray diffraction
Resolution	2.01 - 2.49 Å
Structure data	PDB-3mv5: Crystal structure of Akt-1-inhibitor complexes Method: X-RAY DIFFRACTION / Resolution: 2.47 Å PDB-3mvh: Crystal structure of Akt-1-inhibitor complexes Method: X-RAY DIFFRACTION / Resolution: 2.01 Å PDB-3mvj: Human cyclic AMP-dependent protein kinase PKA inhibitor complex Method: X-RAY DIFFRACTION / Resolution: 2.49 Å
Chemicals	ChemComp-MN: Unknown entry ChemComp-XFE: (3R)-1-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-amine ChemComp-HOH: WATER ChemComp-WFE: N-{[(3S)-3-amino-1-(5-ethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl]methyl}-2,4-difluorobenzamide
Source	homo sapiens (human)
Keywords	TRANSFERASE / kinase inhibitor