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TitleStructural determinants for the inhibitory ligands of orotidine-5'-monophosphate decarboxylase.
Journal, issue, pagesBioorg. Med. Chem., Vol. 18, Page 4032-4041, Year 2010
Publish dateApr 9, 2010 (structure data deposition date)
AuthorsMeza-Avina, M.E. / Wei, L. / Liu, Y. / Poduch, E. / Bello, A.M. / Mishra, R.K. / Pai, E.F. / Kotra, L.P.
External linksBioorg. Med. Chem. / PubMed:20452222
MethodsX-ray diffraction
Resolution1.2 Å
Structure data

PDB-3mi2:
Crystal structure of human orotidine-5'-monophosphate decarboxylase complexed with pyrazofurin monophosphate
Method: X-RAY DIFFRACTION / Resolution: 1.2 Å

Chemicals

ChemComp-PFU:
(1S)-1,4-anhydro-1-(5-carbamoyl-4-hydroxy-1H-pyrazol-3-yl)-5-O-phosphono-D-ribitol

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLYASE / UMP synthase / Orotidine 5'-monophosphate Decarboxylase / pyrazofurin monophosphate

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