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TitleX-ray snapshot of HIV-1 protease in action: observation of tetrahedral intermediate and short ionic hydrogen bond SIHB with catalytic aspartate.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 132, Page 6366-6373, Year 2010
Publish dateNov 10, 2017 (structure data deposition date)
AuthorsDas, A. / Mahale, S. / Prashar, V. / Bihani, S. / Ferrer, J.L. / Hosur, M.V.
External linksJ. Am. Chem. Soc. / PubMed:20397633
MethodsX-ray diffraction
Resolution1.76 Å
Structure data

PDB-5yrs:
X-ray Snapshot of HIV-1 Protease in Action: Observation of Tetrahedral Intermediate and Its SIHB with Catalytic Aspartate
Method: X-RAY DIFFRACTION / Resolution: 1.76 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus 1
KeywordsHYDROLASE / HIV-1 PROTEASE / TETRAHEDRAL INTERMEDIATE / SHORT IONIC HYDROGEN BOND / SUBSTRATE COMPLEX / RT-RH

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