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Structure paper

TitleMigrastatin analogues target fascin to block tumour metastasis.
Journal, issue, pagesNature, Vol. 464, Page 1062-1066, Year 2010
Publish dateJan 29, 2010 (structure data deposition date)
AuthorsChen, L. / Yang, S. / Jakoncic, J. / Zhang, J.J. / Huang, X.Y.
External linksNature / PubMed:20393565
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-3llp:
1.8 Angstrom human fascin 1 crystal structure
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-K:
Unknown entry

ChemComp-BR:
BROMIDE ION

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / beta-trefoil / actin bundling protein / cancer / metastasis / cell migration / Acetylation / Actin-binding / Cytoplasm / Phosphoprotein

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