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Structure paper

TitleGlycal formation in crystals of uridine phosphorylase.
Journal, issue, pagesBiochemistry, Vol. 49, Page 3499-3509, Year 2010
Publish dateNov 26, 2009 (structure data deposition date)
AuthorsPaul, D. / O'Leary, S.E. / Rajashankar, K. / Bu, W. / Toms, A. / Settembre, E.C. / Sanders, J.M. / Begley, T.P. / Ealick, S.E.
External linksBiochemistry / PubMed:20364833
MethodsX-ray diffraction
Resolution1.8 - 2.783 Å
Structure data

PDB-3ku4:
Trapping of an oxocarbenium ion intermediate in UP crystals
Method: X-RAY DIFFRACTION / Resolution: 2.099 Å

PDB-3kuk:
Trapping of an oxocarbenium ion intermediate in UP crystals
Method: X-RAY DIFFRACTION / Resolution: 2.783 Å

PDB-3kvr:
Trapping of an oxocarbenium ion intermediate in UP crystals
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-3kvv:
Trapping of an oxocarbenium ion intermediate in UP crystals
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-3kvy:
Trapping of an oxocarbenium ion intermediate in UP crystals
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-DUR:
2'-DEOXYURIDINE

ChemComp-URF:
5-FLUOROURACIL / medication, chemotherapy*YM

ChemComp-R2G:
2,5-anhydro-4-deoxy-D-erythro-pent-4-enitol

ChemComp-R2B:
1,4-anhydro-D-erythro-pent-1-enitol

ChemComp-URA:
URACIL

Source
  • bos taurus (domestic cattle)
  • escherichia coli (E. coli)
KeywordsTRANSFERASE / Oxocarbenium Ion / Glycal / Pyrimidine Salvage / Uridine Phosphorylase / Cytoplasm / Glycosyltransferase

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