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TitleBiochemical basis of the interaction between cystic fibrosis transmembrane conductance regulator and immunoglobulin-like repeats of filamin.
Journal, issue, pagesJ. Biol. Chem., Vol. 285, Page 17166-17176, Year 2010
Publish dateAug 27, 2009 (structure data deposition date)
AuthorsSmith, L. / Page, R.C. / Xu, Z. / Kohli, E. / Litman, P. / Nix, J.C. / Ithychanda, S.S. / Liu, J. / Qin, J. / Misra, S. / Liedtke, C.M.
External linksJ. Biol. Chem. / PubMed:20351101
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-3isw:
Crystal structure of filamin-A immunoglobulin-like repeat 21 bound to an N-terminal peptide of CFTR
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSTRUCTURAL PROTEIN / protein-peptide complex / Acetylation / Actin-binding / Alternative splicing / Cytoplasm / Cytoskeleton / Disease mutation / Phosphoprotein / Polymorphism / ATP-binding / Chloride / Chloride channel / Glycoprotein / Hydrolase / Ion transport / Ionic channel / Membrane / Nucleotide-binding / Transmembrane / Transport

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