+Search query
-Structure paper
Title | Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design. |
---|---|
Journal, issue, pages | J. Mol. Biol., Vol. 398, Page 497-506, Year 2010 |
Publish date | Mar 23, 2007 (structure data deposition date) |
Authors | Shafqat, N. / Turnbull, A. / Zschocke, J. / Oppermann, U. / Yue, W.W. |
External links | J. Mol. Biol. / PubMed:20346956 |
Methods | X-ray diffraction |
Resolution | 1.7 - 2 Å |
Structure data | PDB-2p8u: PDB-2wya: |
Chemicals | ChemComp-COA: ChemComp-GOL: ChemComp-HOH: ChemComp-HMG: |
Source |
|
Keywords | TRANSFERASE / hydromethylglutaryl CoA / mevalonate pathway / Structural Genomics / Structural Genomics Consortium / SGC / STEROID BIOSYNTHESIS / CHOLESTEROL BIOSYNTHESIS / MITOCHONDRIA / MITOCHONDRION / PHOSPHOPROTEIN / MELAVONATE PATHWAY / STEROL BIOSYNTHESIS / THIOLASE / ACETYLATION / LIPID SYNTHESIS / TRANSIT PEPTIDE / DISEASE MUTATION |